Alzheimer's - CBD (Cannabidiol) Health Benefits

Alzheimers

Cannabidiol (CBD) has shown to be a promising Alzheimer’s aid …



Alzheimer's is progressive mental deterioration that can occur in middle or old age and it's the most common form of dementia. Essentially Alzheimer’s disease is caused by a build up in the brain of 'plaques' and 'tangles'. These 'plaques' and 'tangles' limit the connections between nerve cells, and this eventually to the death of nerve cells and loss of brain tissue.

- Plaques are abnormal clusters of chemically “sticky” proteins called beta-amyloid that build up between nerve cells.

Research has show CBD prevents Alzheimer's plaque…


Cannabidiol (CBD) aids PPAR-gamma activation which degrades amyloid-beta plaque, a key molecule linked to the development of Alzheimer’s disease.

Why is the Amyloid Beta so important when it comes to Alzheimer's disease?

Alzheimer's pathogenesis is widely believed to be driven by the production and deposition of the Amyloid Beta (Amyloid Beta toxicity). In general, intellect, social skills, personality, and memory are influenced by the deposition of the Amyloid Beta.

Can CBD really help Alzheimer's?


CBD (Cannabidiol) gives a neuroprotective, anti-oxidative and anti-apoptotic effect against beta-amyloid peptide toxicity (https://www.ncbi.nlm.nih.gov/pubmed/9216088) , and that inhibition of caspase 3 appearance elevates cell survival while it decreases ROS production, lipid peroxidation, caspase 3 levels, DNA fragmentation and intracellular calcium. Read more about how CBD can prevent Amyloid Beta toxicity.

Alzheimer's Aggression


One of the most common symptoms of Alzheimer's is ‘Aggression’ this type of behavioural symptom is often difficult to deal with by both carers and AD patients. The AD patient is not at fault and although the aggression can flare up at any time there are usually signs that precipitate an outburst like discomfort, lack of sleep and anxiety. There is now research being undertaken to show how CBD may have a calming effect on AD aggression.

CBD as a potential AD treatment for halting and regeneration…


Evidence clearly shows that suppression of excitotoxicity by cannabinoids in addition with neurotrophic benefits could potentially treat AD. As cannabinoids offer neuroprotection they help regulate neurogenesis, recent studies show that cannabinoids also aid in the generation of new neurons by promoting neural progenitor proliferation and healthy neurogenesis.

Watch video about how CBD effects Alzheimer's disease through the endocannabinoid system…